Subjected to human experimentation that transforms Kisaragi into a cyborg, he becomes entangled in a web of pressure from multiple factions. These include an immortal convent of vampires with ambitions to conquer Tokyo, an order of knights seeking eternal life, and a Yakuza group bound by a vow to avenge their slain leader.
With a resolute determination, Kisaragi declares, "I might not have any reason to live, but that's no reason to let them kill me." Faced with this perilous situation, he must leverage his cyborg enhancements, exploit his unique "blood," and employ any means necessary to orchestrate a daring escape from the clutches of these formidable adversaries.